Original research

Cardiohemodynamics Features and Coronary Artery Injury in Patients with Coronary Artery Disease and Comorbide Diabetes Mellitus Type 2 Depending on the Activity of Immune Inflammation Based on the Study of Pentraxin-3 Indicators in Blood Serum

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D. Molotiagin, O. Kadikova, P. Kravchun Kharkiv National Medical University Introduction. Coronary artery disease (CAD) is one of the leading causes of disability and mortality of the population. Diabetes mellitus (DM) is one of the significant risk factors for patients with CAD. There is a need to detect early signs of these diseases and improve the quality Read More …

Substantiation of Principles and Effectiveness of Advanced Complex Differentiated Treatment of Circulatory System Organs Affections in Patients With Liver Cirrhosis

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M. Farmaha1, M. Abrahamovych1, A. Svintsitskyi2, O. Abrahamovych1 1Danylo Halytsky Lviv National Medical University 2Bogomolets National Medical University Introduction. Liver cirrhosis is one of the most important and complex problems of modern hepatology. Comorbid syntrophic affections of liver cirrhosis are also relevant, including circulatory system affection – syntropic cirrhotic cardiomyopathy and persistent arterial hypotension, which Read More …

Content of Some Endothotelium-Dependent Vasoactive Substances in the Blood of Patients, Depending on the Liver Cirrhosis Severity and the Organism’s Redox System State

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M. Abrahamovych, O. Abrahamovych, O. Fayura, S. Tolopko, M. Ferko Danylo Halytsky Lviv National Medical University Introduction. It is known that liver cirrhosis (LC) is a chronic diffuse liver disease, the severity of which is manifested by the restructuring of its parenchyma in the form of nodular transformation and fibrosis due to necrosis of hepatocytes, Read More …

Clinical-genetic and Inter-Genetic Correlation Analysis (with Expression of miRNA-34а) in Patients with Pleomorphic Adenomas of the Salivary Glands

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І. Brodetskyi Bogomolets National Medical University, Kyiv Introduction. The most common tumor remains pleomorphic adenoma – 60.0-90.0 % of all benign tumors of the salivary glands. The modern genetic area of focus in the diagnosis of salivary gland tumors is the study of the role of miRNA molecules. MiRNAs are small non-coding RNAs that regulate Read More …

Diagnostic Value of the Laboratory Markers of Acute Cytomegalovirus Infection in Patients With Systemic Lupus Erythematosus

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U. Abrahamovych, O. Abrahamovych, S. Guta, L. Thyhanyk, O. Romaniuk  Danylo Halytsky Lviv National Medical University Introduction. Systemic lupus erythematosus (SLE) is one of the major medical and social problems, as it is most commonly seen in young people, accompanied by a variety of multiple organ lesions and clinical manifestations that often lead to disability and Read More …

Peculiarities of Social Functioning of Patients With Vascular Dementia, Complicated by Hallucinator-Paranoid Disorders

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K. Shevchenko-Bitensky SI “Ukrainian Research Institute of Medical Rehabilitation and Balneology of Ministry of Health of Ukraine” Introduction. The increasing prevalence of severe cognitive impairment in populations, the involvement of a significant number of people of working age in the medical, economic, psychological and social problems associated with dementia, the decline in social functioning and Read More …

Peculiarities of influence of single intragastric administration of H2-histamine receptor blockers of the second (nisatidine) and third (famotidine) generation on acid-peptic and mucoid-electrolyte secretion of the stomach in patients with duodenal ulcer

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M. Pliatsko Danylo Halytsky Lviv National Medical University Introduction. Antisecretory drugs are commonly used in the complex treatment of most diseases of the upper gastrointestinal tract. Today, proton pomp inhibitors (PPI) have a priority in the basic treatment for acid-dependent diseases of the gastrointestinal tract due to its higher acid-blocking ability. However, PPI have a Read More …

The Basic Principles of Follow-up Patients with Acute Coronary Syndrome in the Precarpathian Region and the Effectiveness of Cardiorehabilitation of These Patients After Myocardial Revascularization

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I. Vakaliuk, R. Nesterak, V. Sovtus Ivano-Frankivsk National Medical University Introduction. Coronary heart disease is the main cause of mortality among diseases of the circulatory system, and the use of myocardial revascularisation contributes to the improvement of the disease course. However, along with the use of high-tech diagnostic and treatment methods, cardio-rehabilitation is an integral Read More …

Peculiarities of Clinical Indices, Duration and Complication of Acute Pancreatitis in Patients With Comorbid Obesity

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A. Kebkalo, O. Tkachuk, A. Reiti Shupyk National Medical Academy of Postgraduate Education Introduction. Obesity is considered a global problem of humanity of the third millennium. According to the World Health Organization, obesity is an epidemic non-infectious disease. About 30.0 % of the planet’s population is overweight or obese. This indicator is progressively increasing, because Read More …

Spectrum of Cortactin Isoforms in the Urine of Patients with Liver Cirrhosis and Their Diagnostic Value as a Potential Molecular Marker of its Severity

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O. Fayura2, M. Starikovych1, O. Abrahamovych2, M. Abrahamovych2, R. Stoyka1, Yu. Kit1 1Department of Regulation of Cell Proliferation and Apoptosis of Institute of Cell Biology of National Academy of Sciences of Ukraine 2Danylo Halytsky Lviv National Medical University Introduction. Non-invasive methods of research of the human organism clinical conditions have been widely used in medicine Read More …