acute pancreatitis

Soluble Fibrin-monomeric Complexes and D-dimers as Indicators of Acute Pancreatitis Severity

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S. Chooklin1, B. Pidhirnyi2, R. Barylyak2 1Danylo Halytsky Lviv National Medical University   Introduction. Local and systemic inflammation, disorders in the hemostatic system are among the key components of acute pancreatitis (AP) pathogenesis already in its early stages, and in future development of thrombohemorrhagic complications. The degree of systemic hemostatic disorders in AP varies from Read More …

Peculiarities of Clinical Indices, Duration and Complication of Acute Pancreatitis in Patients With Comorbid Obesity

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A. Kebkalo, O. Tkachuk, A. Reiti Shupyk National Medical Academy of Postgraduate Education Introduction. Obesity is considered a global problem of humanity of the third millennium. According to the World Health Organization, obesity is an epidemic non-infectious disease. About 30.0 % of the planet’s population is overweight or obese. This indicator is progressively increasing, because Read More …

Efficiency of the Original Methods of Using Medicines and Early Enteral Nutrition in the Complex Treat­ Ment of Patients with Acute Pancreatitis

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V. Andryushchenko, D. Andryushchenko, V. Kunovsky, V. Mahlovany  Danylo Halytsky Lviv National Medical University Introduction. In addition to the implementation of adequate surgical tactics, the non­interventional component of treatment, aimed at correcting mechanisms for the appearance and increase of the severity of acute pancreatitis, becomes more and more important. The aim of the study. To Read More …

Peculiarities of Inflammation, Oxidative/Nitrosative Stress in L-Ornithine-Induced Acute Pancreatitis

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S. Chooklin, S. Chuklin, G. Shershen Lviv Regional Clinical Hospital Introduction. The pathogenesis of acute pancreatitis (AP) continues to be a mystery to scientists. However, significant achievements in the field of fundamental research in the last decade have improved the information on pathophysiological processes in the AP. However, despite the progress in understanding early events Read More …

Heparins: Mechanism of Action and Application in Acute Pancreatitis

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S. Chooklin, B. Pidhirnyy, S. Chuklin Lviv Regional Clinical Hospital Introduction. Heparin is a glycosaminoglycan composed of chains of alternating d-glucosamine and uronic acid residues. Its major anticoagulant effect is attributed to a unique pentasaccharide structure. Heparin prevents coagulation after binding with a plasma antithrombin III. Antithrombin III is a protease inhibitor and complex heparin Read More …

С.М. Чуклін, О.Б. Гранат

The Role of Proinflammatory Cytokines and Adhesion Molecules in Vascular Disorders and Organ Dysfunction in Acute Pancreatitis Patients

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S. Chooklin1, O. Hranat2 1Danylo Halytsky Lviv National Medical University 2Lviv Regional Clinical Hospital Introduction. The incidence of acute pancreatitis (AP) in the world has increased over the last years, mainly due to alcohol consumption. The increasing of the AP severity is characterized by pancreatic necrosis, local complications and systemic organ dysfunction and is about Read More …