inflammation

The Role of Intestinal Microbiota, Endotoxemia and Systemic Inflammation in the Pathogenesis of Nonalcoholic Fatty Liver Disease

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G. Fadieienko, А. Gridnev, I. Kushnir, T. Solomentseva, V. Chernova, V. Galchіnskaya Government Institution “L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine” (GI “L.T.Mala NIT NAMSU”) Introduction. Currently there are few and contradictory data concerning the influence of intestinal microbiota (IM) disturbances on the nature and severity of inflammatory processes Read More …

Peculiarities of Inflammation, Oxidative/Nitrosative Stress in L-Ornithine-Induced Acute Pancreatitis

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S. Chooklin, S. Chuklin, G. Shershen Lviv Regional Clinical Hospital Introduction. The pathogenesis of acute pancreatitis (AP) continues to be a mystery to scientists. However, significant achievements in the field of fundamental research in the last decade have improved the information on pathophysiological processes in the AP. However, despite the progress in understanding early events Read More …

Heparins: Mechanism of Action and Application in Acute Pancreatitis

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S. Chooklin, B. Pidhirnyy, S. Chuklin Lviv Regional Clinical Hospital Introduction. Heparin is a glycosaminoglycan composed of chains of alternating d-glucosamine and uronic acid residues. Its major anticoagulant effect is attributed to a unique pentasaccharide structure. Heparin prevents coagulation after binding with a plasma antithrombin III. Antithrombin III is a protease inhibitor and complex heparin Read More …