statins

Features of Lipid Spectrum and Insulin Resistance Parameters in Patients with Type 2 Diabetes Mellitus and Cardiac Autonomic Neuropathy and Appropriateness of Simvastatin and Omega-3 Polyunsaturated Fatty Acids Combined Prescription

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S. Azhmi, V. Serhiyenko Danylo Halytsky Lviv National Medical University Introduction. Cardiovascular autonomic neuropathy (CAN) is a serious and common complication of type 2 diabetes mellitus (T2DM). Despite its relationship to an increased risk of cardiovascular mortality and its association with multiple symptoms and impairments, the significance of CAN has not been fully appreciated. CAN Read More …

The Influence of Performance Therapy with Statins on Androgen Balance in Patients with Stable Angina in Combination with Type 2 Diabetes Mellitus

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O. Kapustynska Danylo Halytsky Lviv National Medical University Introduction. Since cholesterol is a substrate for the synthesis of sex hormones, including testosterone, changes in androgen availability in patients taking statins can be expected. At the same time, the effect of statins on androgenic provision of patients with coronary artery disease was studied selectively, mainly in Read More …

О. С. Капустинська

The Influence of Performance Therapy with Statins on Androgen Balance in Patients with Stable Angina in Combination with Type 2 Diabetes Mellitus

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О. Kapustуnskа Тhe present paper analyzes the influence of the HMG-CoA reductase inhibitors (statins) on androgen balance in 120 patients with stable angina (SА) combined with the diabetes mellitus (DM). It demonstrates the definition of the levels of total testosterone (TT), testosterone-estradiol binding globulin (TEBG) in plasma and free androgen index calculation (FAI) = TT•100/TEВG. Read More …