Indicators of Calcium-phosphorus Metabolism and Bone Remodeling as Risk Factors for Bone Mineral Density Disorders in Patients with Rheumatoid Arthritis

V. Chemes, O. Abrahamovych, U. Abrahamovych, O. Fayura, N. Drobinska, L. Kobak Danylo Halytsky Lviv National Medical University Introduction. Osteoporosis (OP) is one of the most common causes of disability decrease in life expectancy among the elderly. The main risk factors for the occurrence of osteoporosis in patients with rheumatoid arthritis (RA) include family predisposition, female sex, Read More …

Calcium-phosphorus metabolism and markers of its regulation in patients with rheumatoid arthritis with violation of bone mineral density: character and diagnostic value

V. Chemes, O. Abrahamovych, U. Abrahamovych, R. Ivanochko, L. Kobak Danylo Halytsky Lviv National Medical University Introduction. Patients with rheumatoid arthritis (RA) are twice as likely to have osteoporosis (OP) compared to the general population. The strength of bones depends on mineral substances, mainly represented by calcium phosphate microcrystals. The chief role in the regulation Read More …

Translation, Cross-Cultural Adaptation and Validation of the Central Sensitization Inventory for Patients with Rheumatoid Arthritis

M. Stanislavchuk, V. Bombela, Y. Shkarivskyy National Pirogov Memorial Medical University, Vinnytsya Introduction. Pain syndrome is one of the leading disabilitating factors in patients with rheumatoid arthritis (RA). Recently the heterogeneity of pathogenetic mechanisms of pain formation in the patients with joints inflammatory diseases has been demonstrated. The phenomenon of central sensitization is among the Read More …

Frequency and Nature of Bone Lesions in Patients with Rheumatoid Arthritis Detected by Ultrasound and X-ray Оsteodensitometry, their Diagnostic Value in Assessing Bone Mineral Density

V. Chemes, U. Abrahamovych, L. Tsyhanyk, S. Guta Danylo Halytsky Lviv National Medical University Introduction. Rheumatoid arthritis (RA) is an unknown etiology of complex autoimmune pathogenesis, a chronic systemic connective disease that is often complicated by secondary osteoporosis (OS), which worsens the course and prognosis of the underlying disease. The aim of the study. To Read More …

Pathogenetic Mechanisms of the Occurrence of Rheumatoid Arthritis and Ankylosing Spondylitis with the Activation-Enzymatic and Phenotypic Features of Lymphocytes

N. Lychkovska, V. Chopyak, Z. Vorobets Danylo Halytsky Lviv National Medical University Introduction. Significant prevalence of inflammatory diseases of the j oints, the tendency to steady increase in their severity, high indicators due to this temporary disability and disability, especially those of middle-aged, determine the important medical and social importance of these diseases. At the Read More …

Influence of Vitamin D Deficiency on the Rheumatoid Arthritis Activity and the Ways of Its Corrections

O. Synenky Lviv Regional Clinical Hospital Introduction. Vitamin D deficiency (VDD) is a global problem of humanity. In Ukraine it is registered in 81.8 % of the adult population. In its turn, rheumatoid arthritis (RA) is the most common disease among the rheumatic diseases of the population of the Lviv region, therefore, the study of Read More …

25(OH)D Level in Patients with Polyarticular Form of Rheumatoid Arthritis and its Dependence on Certain Clinically Significant Parameters

O. Synenkyi Lviv Regional Clinical Hospital Introduction. Vitamin D has multiple physiological functions in the human organism and is associated with the pathogenesis of several autoimmune diseases including rheumatoid arthritis. The aim of the study was to evaluate the the level of 25(OH)D in the serum of patients with polyarticular form of rheumatoid arthritis and Read More …

Functional Activity Indicators of Phagocytic Cells in Peripheral Blood of Patients Diagnosed with Rheumatoid Arthritis Combined with Hypertension and its Change Under the Influence of Treatment

V. Pekhenko Bogomolets National Medical University, Kyiv Introduction. The ratio of spontaneous vs. induced NBT-test neutrophils and monocytes is a reliable diagnostic criterion for evaluating the functional capacity of cells in the system of natural resistance. Thus the goal of our research was to determine the functional activity of phagocytic peripheral blood cells and changes Read More …

Fibromyalgia as a Modifying Factor of Clinical Course of Rheumatoid Arthritis

L. Perebetyuk  National Pirogov Memorial Medical University, Vinnytsya Introduction. Rheumatoid arthritis (RA) is one of the most common inflammatory joint disease, with a progressing severity and high disability. It is often combined with fibromyalgia (FM), which can modify its course. The prevalence of primary FM among adults is on average 2.0-3.0 %, with prevalence of Read More …

New Treatment Possibilities for Patients with Rheumatoid Arthritis Combined with Anxiety and Depressive Disorders

B. Rebrov, S. Kasynets, O. Komarova Lugansk State Medical University Introduction. Patients with rheumatoid arthritis (RA) suffer from psychosocial maladaptation due to pain syndrome, limitation of activity with loss of ability to work and social connections. The presence of anxiety-depressive disorders (ADD) increases the incapacity of patients with RA in the first five years of Read More …