Original research

Structural and Functional Peculiarities of Cardiac Changes in Non-Alcoholic Fatty Liver Disease Patients With Different Polymorphic Variants of the Deletion Polymorphism of the Glutathione-S-Transferase M1 Gene

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V. Prysyazhnyuk, T. Ilashchuk, L. Sydorchuk, P. Prysyazhnyuk, K. Bobkovych, N. Bachuk–Ponych Bukovinian State Medical University Introduction. Epidemiological studies indicate a higher incidence of adverse cardiovascular events in patients with non-alcoholic fatty liver disease (NAFLD) as compared to the general population. In the case of a comorbid combination of liver and cardiovascular diseases, the natural course of Read More …

Treatment of Patients With Vertical Maxillary Excess: Orthognathic Surgery vs Strategic Implant® (Clinical Cases Report)

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A. Ihde1, A. Chakranarayan2, O. Sipic3, P. Soni2, S. Ihde4, Y. Vares5 1International Implant Foundation, Munich, Germany 2Dental Centre, INHS Kalyani, Eastern Naval Command 3International Implant Foundation, Department of Evidence and Research, Munich, Germany 4International Implant Foundation, Department of Evidence and Research, Munich, Germany 5Danylo Halytsky Lviv National Medical University, Department of Maxillofacial Surgery Introduction. Read More …

Features of Cerebral Hemorrhage in the Victims of Peaceful Territory and Fighters of the Operation of the Combined Forces – of the Antiterrorist Operation After Traumatic Brain Injury of Mild Severity in Acute, Intermediate and Distant Periods

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V. Shevaga, M. Semchyshyn, B. Zadorozhna, A. Zadorozhnyi Danylo Halytsky Lviv National Medical University Introduction. Craniocerebral trauma determines its place among the priority areas of modern clinical neurology. Brain injuries along with dystrophic processes cause disorders of cerebral hemodynamics and vascular tone, which are significant and are important factors in the pathogenesis of neurological symptoms Read More …

Features of the State of Internal Organs and the Structure of Comorbidity in Deceased Persons With Alcoholic Liver Cirrhosis, Non-alcoholic Fatty Liver Disease at the Cirrhosis Stage and Alcoholic Liver Cirrhosis Associated With Insulin Resistance and Obesity

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N. Matkovska Ivano-Frankivsk National Medical University Introduction. Today, the most common pathologies among the chronic diffuse liver diseases is non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease. The aim of the study. The aim of the work was to study the peculiarities of the the state of internal organs in deceased persons with alcoholic Read More …

Redox Homeostasis Index as a Criterion for Differentiated Inclusion of Antioxidants in Complex Treatment of the Patients with Liver Cirrhosis of Different Severity Degrees and Evaluation of Its Effectiveness

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O. Fayura1, M. Abrahamovych1, O. Abrahamovych1, L. Fayura2 1Danylo Halytsky Lviv National Medical University 2Institute of Cell Biology of the National Academy of Sciences of Ukraine Introduction. The course of liver cirrhosis (LC) is determined by the appearance and increase of the severity of syntropic comorbid lesions caused by the redox homeostasis disorders with the prooxidants Read More …

Effectiveness of in Vitro Fertilization Treatment in the Presence of Chronic Endometritis

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L. Markin1, L. Sehedii2 1Danylo Halytsky Lviv National Medical University 2Human Reproduction Clinic ʺAlternatyvaʺ Introduction. For today, reproductive disorders are an urgent problem not only in Ukraine, but all over the world. Finding out the causes of these conditions is a prerequisite for improving existing treatments. Unfortunately, even using the latest advances in reproductology, it Read More …

The Efficiency of Complex Differential Treatment of the Patients with Systemic Lupus Erythematous Considering the Features of Bone Tissue Structure Remodeling

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U. Abrahamovych, L. Tsyhanyk, O. Abrahamovych, M. Farmaha, O. Romanyuk  Danylo Halytsky Lviv National Medical University Introduction. Systemic lupus erythematous (SLE) is an autoimmune disease with peculiar plural and pathological processes in different organs and systems including bone tissue. Patient’s physiological, social and psychological states depend on the degree of damage of bone system. Nowadays, Read More …

Psychological Risk Factors for Mental Disorders Development in Internally Displaced Persons

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N. Maruta, H. Kalens’ka, V. Fedchenko, T. Pan’ko, O. Maruta State Institution “Institute of Neurology, Psychiatry and Narcology of the National Academy of Medical Sciences of Ukraine” Introduction. Today, the problem of internally displaced persons is one of the most acute for Ukraine. Due to the prolonged military conflict in the Donbass, the occupation of Read More …

Characteristics of Types of Electroencephalograms in Patients with Cerebral Contusion of Mild Severity in the Acute Period with Subarachnoid and without Subarachnoid Hemorrhage

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V. Shevaga, M. Semchyshyn, B. Zadorozhna, A. Zadorozhnyi Danylo Halytsky Lviv National Medical University Introduction. The proportion of brain injury is steadily increasing every year, remaining not only a medical but also a social problem, since it requires considerable economic costs both for diagnosis and treatment and for social rehabilitation of the victims. The common Read More …

CYP2C9 Polymorphism Study in Patients with Acute Back Pain and its Impact on the Effectiveness of Treatment with the Non-Steroidal Anti-Inflammatory Drugs

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I. Maslova1, N. Mykhailovska2, T. Slobodin2 1MOTOR SICH medical facility, Zaporizhzhia 2Shupyk National Medical Academy of Postgraduate Education, Kyiv Introduction. Genetic factors can generate different variants of physiological responses to non-steroidal anti­inflammatory drugs (NSAIDs) – from the complete ineffectiveness of medicines to the appearance of adverse reactions. The presence of mutant alleles of the gene Read More …