Original research

Evaluation of Cytokines and Biomarkers of Inflammation Indices in Patients with Peritoneal Sepsis with Different Degrees of Severity

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O. Plytka I. Horbachevsky Ternopil National Medical University Introduction. Sepsis, severe sepsis and septic shock are major public health problems worldwide. The consequences of sepsis are especially unfavorable for people with weakened immunity. Biomarkers of inflammation play an important role in the diagnosis of sepsis: C-reactive protein and procalcitonin, the indices of which increase significantly in Read More …

The Nature and Frequency of Comorbid Heart Lesions in Patients with Systemic Lupus Erythematosus Diagnosed by Echocardiography, Detection and Characteristics of Their Syntropic Variants

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L. Kobak, O. Abrahamovych, U. Abrahamovych, S. Guta,L. Tsyhanyk Danylo Halytsky Lviv National Medical University Introduction. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by damage of different organs and systems. It has been proven that cardiovascular events are proportionally more frequent in SLE compared to the general population of the corresponding age and sex. Echocardiography Read More …

Indicators of Calcium-phosphorus Metabolism and Bone Remodeling as Risk Factors for Bone Mineral Density Disorders in Patients with Rheumatoid Arthritis

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V. Chemes, O. Abrahamovych, U. Abrahamovych, O. Fayura, N. Drobinska, L. Kobak Danylo Halytsky Lviv National Medical University Introduction. Osteoporosis (OP) is one of the most common causes of disability decrease in life expectancy among the elderly. The main risk factors for the occurrence of osteoporosis in patients with rheumatoid arthritis (RA) include family predisposition, female sex, Read More …

The Results of Dynamometry in Assessing the Mechanical Strength of Scar Tissue with Different Options for Surgical Wound Closure

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H. Zhurakovska, V. Malanchuk Bogomolets National Medical University Introduction. Scar formation in the area of traumatic skin damage is a heterogeneous process and is characterized by the presence of certain biomechanical (elasticity, tensile strength, tensile strength) and morphological (healing by primary tension, secondary tension, under a scab, complicated wounds) features that may not simply affect Read More …

Effectiveness of Complex Medical Treatment Using L-carnitine and Dapagliflozin in Patients with ST-Segment Elevation Myocardial Infarction and Comorbid Type 2 Diabetes Mellitus

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M. Shved, R. Ovsiychuk Ivan Horbachevsky Ternopil National Medical University Introduction.Patients with type 2 diabetes mellitus (T2DM) have a 2-fold increased risk of coronary heart disease, and the risk of death from it is 2-4 times higher than in patients without carbohydrate metabolism disorders. The reason for such negative trends is considered to be the Read More …

The difference of anxiety, depression and cortisol levels in patients with acute and chronic vertebrogenic lumbosacral pain syndrome

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A. Payenok, A. Kulyk Danylo Halytsky Lviv National Medical University Introduction. Pain is classified as acute and chronic. Acute pain implies a painful condition with a rapid onset or of a short course, whereas chronic pain is referred to as a painful condition persisting beyond the normal time of healing. Chronic low back pain has Read More …

The Relationships between the Problems with Somatic Health in Preschool Children and Disorders of Psychomotor Development

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А. Pushnyk, S. Niankovskyy Danylo Halytsky Lviv National Medical University Introduction. Multiple studies show the presence of interconnection between co-morbidity and psychomotor development disorders in children. The aim of the study. To identify the relationships between the problems with somatic health in preschool children (3-7 years old) and disorders of their psychomotor development. Materials and Read More …

Classification and Ranking of Factors Affecting the Quality of Tactile Perception of L. Braille Font by Blind People

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M. Havenko1, M. Labetska2, V. Korotka3 1Lviv Regional Clinical Hospital 2Ukrainian Academy of Printing 3Andrei Krupynskyi Lviv Medical Academy Introduction. In the process of educational and work activities, blind people mostly use tactile sensitivity to perceive information, the presentation of which is mainly realized in a six-dot format according to the well-known Braille system. The Read More …

Peculiarities of Bone Mineral Density in Men with Ankylosing Spondylitis: Frequency and Nature of Disorders; Content in Blood Serum of Metabolic Indicators of Synthesis and Resorption of Bone Tissue, Vitamin D; Reliable Factors Involved in its Violations

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O. Pavliuk1, L. Marynych1, L. Denishchich1, I. Kuvikova2, O. Shevchuk1 1National Pirogov Memorial Medical University, Vinnytsya 2Research Institute of Rehabilitation of Persons with Disabilities National Pirogov Memorial Medical University, Vinnytsya Introduction. Decreased bone mineral density (BMD) and the development of osteoporosis are common and poorly understood complications of ankylosing spondylitis (AS). Increased bone turnover and Read More …

The Role of Intestinal Microbiota, Endotoxemia and Systemic Inflammation in the Pathogenesis of Nonalcoholic Fatty Liver Disease

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G. Fadieienko, А. Gridnev, I. Kushnir, T. Solomentseva, V. Chernova, V. Galchіnskaya Government Institution “L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine” (GI “L.T.Mala NIT NAMSU”) Introduction. Currently there are few and contradictory data concerning the influence of intestinal microbiota (IM) disturbances on the nature and severity of inflammatory processes Read More …