The Nature and Frequency of Comorbid Heart Lesions in Patients with Systemic Lupus Erythematosus Diagnosed by Echocardiography, Detection and Characteristics of Their Syntropic Variants

L. Kobak, O. Abrahamovych, U. Abrahamovych, S. Guta,L. Tsyhanyk Danylo Halytsky Lviv National Medical University Introduction. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by damage of different organs and systems. It has been proven that cardiovascular events are proportionally more frequent in SLE compared to the general population of the corresponding age and sex. Echocardiography Read More …

Circulatory System Organs Comorbid Lesions in Patients with Systemic Lupus Erythematosus: Nature and Frequency; Characteristics Depending on Gender, Age and Disease Duration

L. Kobak, O. Abrahamovych, U. Abrahamovych, R. Ivanochko, V. Chemes Danylo Halytsky Lviv National Medical University Introduction. Systemic lupus erythematosus (SLE) is a disease with numerous clinical manifestations and an unpredictable course. It often lasts for several months or years, with alternating remissions and exacerbations. Multiple organs can be affected simultaneously with varying degrees of Read More …

Frequency of Necessary Clinical and Laboratory Diagnostic Criteria for Systemic Lupus Erythematosus in the Presence of Active Cytomegalovirus and M. A. Epstein – Y. Barr Virus and Their Diagnostic Value

S. Guta, O. Abrahamovych, U. Abrahamovych, L. Tsyhanyk, V. Chemes Danylo Halytsky Lviv National Medical University Introduction. Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology, in the origin and pathogenesis of which cytomegalovirus (CMV) and M. A. Epstein – Y. Barr virus (EBV) play an important role. There is a need to Read More …

The Efficiency of Complex Differential Treatment of the Patients with Systemic Lupus Erythematous Considering the Features of Bone Tissue Structure Remodeling

U. Abrahamovych, L. Tsyhanyk, O. Abrahamovych, M. Farmaha, O. Romanyuk  Danylo Halytsky Lviv National Medical University Introduction. Systemic lupus erythematous (SLE) is an autoimmune disease with peculiar plural and pathological processes in different organs and systems including bone tissue. Patient’s physiological, social and psychological states depend on the degree of damage of bone system. Nowadays, Read More …

Diagnostic Value of the Laboratory Markers of Acute Cytomegalovirus Infection in Patients With Systemic Lupus Erythematosus

U. Abrahamovych, O. Abrahamovych, S. Guta, L. Thyhanyk, O. Romaniuk  Danylo Halytsky Lviv National Medical University Introduction. Systemic lupus erythematosus (SLE) is one of the major medical and social problems, as it is most commonly seen in young people, accompanied by a variety of multiple organ lesions and clinical manifestations that often lead to disability and Read More …

Analysis of Markers of Bone Remodeling and Systemic Lupus Erythematosus Activity Index Interconnections

L. Tsyhanyk, O. Abrahamovych, U. Abrahamovych, O. Romanyuk, S. Guta Danylo Halytsky Lviv National Medical University Introduction. Systemic Lupus Erythematosus (SLE) is an autoimmune systemic disease, which is characterized by multiple organ disorders, in particular – bones. The development of osteoporosis (OP) is an extended process and even the complicated aggravation does not have enough Read More …

The Analysis of the Effect of Systemic Lupus Erythematosus Selected Indicators and Its Treatment on Bone Mineral Density

L. Tsyhanyk, U. Abrahamovych, O. Romaniuk Danylo Halytsky Lviv National Medical University Introduction. The lesions of the bone and joint system start to appear during the first ten years of disease in 25.0 % of patients with SLE. The prevalence of osteopenia ranges from 4.0 to 74.0 % and the prevalence of osteoporosis – from Read More …

Herpesviruses in Patients With Systemic Lupus Erythematosus (Literature Review and Clinical Cases Description)

U. Abrahamovych, O. Abrahamovych, S. Guta Danylo Halytsky Lviv National Medical University Introduction. Systemic lupus erythematosus is one of the autoimmune diseases prevailing in women of reproductive age and is, quite often, the cause of their disability. In recent years, the attention of researchers has been focused on clarifying the role of herpesviruses in origin, Read More …

Characteristics of the Autonomic Nervous System State in Patients with Systemic Lupus Erythematosus with the Different Activity Degree According to the Indices of Heart Rate Variability

U. Abrahamovych Danylo Halytsky Lviv National Medical University Introduction. Vegetative disorders are a term that unites varieties of origin and manifestations of the violation of vegetative functions of the organism, which are caused by the disorders of their neurogenic regulation. Regarding the pathogenesis of the autonomic nervous system (NS) dysfunction in the presence of systemic Read More …

Сomparative Evaluation of Bone Mineral Density Based upon the Results of Ultrasound Osteodensitometry, X-ray Osteodensitometry, and Dual-Energy X-ray Absorptiometry Tests in Premenopausal Women with Systemic Lupus Erythematosus

U. Abrahamovych1, O. Abrahamovych1, L. Tsyhanyk1, O. Synenkyi2, S. Guta1 1Danylo Halytsky Lviv National Medical University 2Lviv Regional Clinical Hospital Introduction. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the chronic inflammation and multisystemic damages, accompanied by lesions in osteoarticular system, including secondary osteoporosis (OP) ­ an important risk factor for low­energy fractures. Read More …