Clinical characteristics of patients with obesity associated with bronchial asthma, depending on the age of onset

V. Kachkovska Sumy State University  Introduction. Previous studies have identified two primary phenotypes of bronchial asthma (BA) associated with obesity: early atopic and late without atopy. These phenotypes differ in age of onset, pathogenic mechanisms of development, and response to basic treatment. The aim of present study was to analyze clinical and anamnestic data of Read More …

Contemporary perspectives on vitamin D provision in children and adolescents with obesity: a literature review and clinical case description

M. Yatsula, S. Nyankovskyy Danylo Halytsky Lviv National Medical University Introduction. Vitamin D deficiency is currently considered a global epidemic. Recent data highlight its pivotal role in the development of metabolic disorders, including obesity in children and adolescents. The aim of the study. To review current literature on the problem of vitamin D provision in Read More …

Activity of Arginine/Citruline Cycle Enzymes and Their Association with Laboratory-Biochemical Indicators of Liver Injury in Patients with Acute Lymphoblastic Leukemia

G. Maslova, I. Skrypnyk, T. Lymanets Ukrainian Medical Stomatological Academy Introduction. The onset of acute lymphoblastic leukemia (ALL) is accompanied by liver injury, which may be due to chemotherapy, tumor infiltration of liver tissue, intoxication. The study of pathogenetic features of liver injury development in patients with oncohematological diseases may be important for their management. Read More …

Peculiarities of Clinical Indices, Duration and Complication of Acute Pancreatitis in Patients With Comorbid Obesity

A. Kebkalo, O. Tkachuk, A. Reiti Shupyk National Medical Academy of Postgraduate Education Introduction. Obesity is considered a global problem of humanity of the third millennium. According to the World Health Organization, obesity is an epidemic non-infectious disease. About 30.0 % of the planet’s population is overweight or obese. This indicator is progressively increasing, because Read More …

Content of Angiogenesis Markers of Insulin-Like Growth Factor-1 and Endostatin in Patients with Acute Myocardial Infarction in the Presence or Absence of Comorbid Obesity

D. Martovytskyi, O. Shelest, P. Kravchun Kharkiv National Medical University Introduction. The study of markers which would improve the stratification of risk and diagnosis of acute myocardial infarction, is of great importance. The aim of the study. To investigate the content of angiogenesis markers insulin-like growth factor-1 and endostatin in patients with acute myocardial infarction Read More …

Features of Glucose Homeostasis and Blood Lipid Spectrum in Patients with Nonalcoholic Fatty Liver Dis­ ease Depending on the Obesity Degree

I. Korniichuk1, O. Khukhlina2, V. Vivsyannuk2, O. Yatskevych1, І. Kovalska1 1Danylo Halytsky Lviv National Medical University 2Bukovinian State Medical University Introduction. The increase of the number of obese patients is growing steadily not only in Ukraine but also in the world. In the economically developed countries, almost 50.0 % of the population are overweight, including Read More …

The Effects of Dual Antiplatelet Therapy on the Occurrence of Recurrent Cardiovascular Events After Myocardial Infarction in Obese Patients

K. Borovyk, N. Rindina, P. Kravchun, O. Tabachenko, O. Yermak, M. Romanyuk Kharkiv National Medical University Introduction. Acute myocardial infarction (AMI) with ST elevation (STEMI) is still the main cause of mortality and invalidisation of able­bodied population. Regardless of the primary percutaneous coronary intervention (PCI) or thrombolysis, dual antiplatelet therapy (DAPT) remains the main therapeutic Read More …

Dislipidemia and Serum Level of Interleukin-22 in Hyptrtensive Patients with Concomitant Excessive Body Weight or Obesity

O. Kovalyova, T. Ashcheulova, K. Kysylenko Kharkiv National Medical University Introduction. Hypertension is the most common chronic disease that has up to 20.0-30.0 % of the adult population of the planet. The presence of concomitant diseases, including obesity worsens the course and prognosis of Hypertension. Therefore, one of the pressing and studying problems at this Read More …

Sleep Disorders and Risk Factors of Obstructive Sleep Apnea Syndrome in Hypertensive Patients with Obesity in the Practice of Physician-Internist

O. Radchenko, N. Bek, I. Zvorska, R. Mykulynets Danylo Halytsky Lviv National Medical University Introduction. Obstructive sleep apnea (OSA) – a condition accompanied repeated, stop of breathing due to complete (apnea) or partial (hypopnea) narrowing of the airways during sleep at throat and termination of pulmonary ventilation with preserved respiratory effort which appears snoring, reduced Read More …

The Role of Gene of the Tumor Necrosis factor-alfa G-308A Polymorphism in the Development of Congestive Heart Failure in Patients with Ischemic Heart Disease and Obesity

P. Kravchun, O. Kadykova, N. Ryndina, S. Krapivko Kharkiv National Medical University Introduction. One of the widespread and prognostically unfavourable conditions in cardiovascular diseases is a congestive heart failure (CHF), where an important role is given to the proinflammatory cytokines in the pathogenesis of the disease. Polymorphic variants of the gene of tumor necrosis factor-a Read More …