Syntropic Lesions of the Cardiovascular System in Patients With Liver Cirrhosis: Their Determination; Selected Pathogenetic Mechanisms; Characteristics and Specifics; Clinical Markers, Their Prognostic Value; Justification and Effectiveness of Modified Treatment (First Notice)

M. Farmaha, M. Abrahamovych, O. Abrahamovych Danylo Halytsky Lviv National Medical University Introduction. Comorbid syntropic lesions of the circulatory system in patients with liver cirrhosis, although often fatal, are poorly studied. The aim of the study. To distinguish syntropic lesions of the cardiovascular system in patients with liver cirrhosis, to determine some of their pathogenetic Read More …

Liver Cirrhosis: Modern Approach to the Problem

T. Bentsa Shupyk National Medical Academy of Postgraduate Education Introduction. Liver cirrhosis (LC) is an important medical and socio-economic problem not only in Ukraine, but throughout the world. The urgency of this disease is due to its significant spread, increase of the number of etiological factors, as well as the occurrence of severe complications, which Read More …

Features of the State of Internal Organs and the Structure of Comorbidity in Deceased Persons With Alcoholic Liver Cirrhosis, Non-alcoholic Fatty Liver Disease at the Cirrhosis Stage and Alcoholic Liver Cirrhosis Associated With Insulin Resistance and Obesity

N. Matkovska Ivano-Frankivsk National Medical University Introduction. Today, the most common pathologies among the chronic diffuse liver diseases is non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease. The aim of the study. The aim of the work was to study the peculiarities of the the state of internal organs in deceased persons with alcoholic Read More …

Redox Homeostasis Index as a Criterion for Differentiated Inclusion of Antioxidants in Complex Treatment of the Patients with Liver Cirrhosis of Different Severity Degrees and Evaluation of Its Effectiveness

O. Fayura1, M. Abrahamovych1, O. Abrahamovych1, L. Fayura2 1Danylo Halytsky Lviv National Medical University 2Institute of Cell Biology of the National Academy of Sciences of Ukraine Introduction. The course of liver cirrhosis (LC) is determined by the appearance and increase of the severity of syntropic comorbid lesions caused by the redox homeostasis disorders with the prooxidants Read More …

Substantiation of Principles and Effectiveness of Advanced Complex Differentiated Treatment of Circulatory System Organs Affections in Patients With Liver Cirrhosis

M. Farmaha1, M. Abrahamovych1, A. Svintsitskyi2, O. Abrahamovych1 1Danylo Halytsky Lviv National Medical University 2Bogomolets National Medical University Introduction. Liver cirrhosis is one of the most important and complex problems of modern hepatology. Comorbid syntrophic affections of liver cirrhosis are also relevant, including circulatory system affection – syntropic cirrhotic cardiomyopathy and persistent arterial hypotension, which Read More …

Content of Some Endothotelium-Dependent Vasoactive Substances in the Blood of Patients, Depending on the Liver Cirrhosis Severity and the Organism’s Redox System State

M. Abrahamovych, O. Abrahamovych, O. Fayura, S. Tolopko, M. Ferko Danylo Halytsky Lviv National Medical University Introduction. It is known that liver cirrhosis (LC) is a chronic diffuse liver disease, the severity of which is manifested by the restructuring of its parenchyma in the form of nodular transformation and fibrosis due to necrosis of hepatocytes, Read More …

Spectrum of Cortactin Isoforms in the Urine of Patients with Liver Cirrhosis and Their Diagnostic Value as a Potential Molecular Marker of its Severity

O. Fayura2, M. Starikovych1, O. Abrahamovych2, M. Abrahamovych2, R. Stoyka1, Yu. Kit1 1Department of Regulation of Cell Proliferation and Apoptosis of Institute of Cell Biology of National Academy of Sciences of Ukraine 2Danylo Halytsky Lviv National Medical University Introduction. Non-invasive methods of research of the human organism clinical conditions have been widely used in medicine Read More …

Severity Degrees of Syntropic Stable Arterial Hypotension in the Cirrhotic Patients and Their Dependence on the Daily Blood Pressure Monitoring and Liver Damage Class by C.G. Child – R.N. Pugh

M. Abrahamovych, M. Farmaha, O. Abrahamovych, O. Fayura, N. Drobinska Danylo Halytsky Lviv National Medical University Introduction. Daily monitoring of the arterial blood pressure in the cirrhotic patients is used in the practical medicine, as well as in numerous scientific studies for the study of the pathogenesis, clinical and instrumental manifestations of the circulatory system Read More …

Clinical Markers of the Syntropic Comorbid Lesions of the Circulatory System in Patients with Liver Cirrhosis

M. Abrahamovych, M. Farmaha Danylo Halytsky Lviv National Medical University Introduction. Syntropic comorbid disorders of the circulatory system in patients with liver cirrhosis are among the most common ones and include two separate diseases: cardiomyopathy with characteristic changes of the heart structure and function; and stable arterial hypotension with its characteristic features of daily blood Read More …

Peculiarities of Calcium-Phosphorus Metabolism and Bone State in Patients with Liver Cirrhosis: Diagnosis and Principles of Differential Treatment (Literature Rewiev and Clinical Case Description)

N. Drobinska, O. Abrahamovych, U. Abrahamovych, M. Farmaha Danylo Halytsky Lviv National Medical University Introduction. The disorders of calcium-phosphorus metabolism and bone tissue state, which are the main cause of spontaneous fractures and motor activity disorders in patients with liver cirrhosis, they require deeper understanding of etiology and pathogenesis, the use of laboratory-instrumental methods of Read More …