The Analysis of the Effect of Systemic Lupus Erythematosus Selected Indicators and Its Treatment on Bone Mineral Density

L. Tsyhanyk, U. Abrahamovych, O. Romaniuk Danylo Halytsky Lviv National Medical University Introduction. The lesions of the bone and joint system start to appear during the first ten years of disease in 25.0 % of patients with SLE. The prevalence of osteopenia ranges from 4.0 to 74.0 % and the prevalence of osteoporosis – from Read More …

Characteristic of Calcium and Phosphorus Homeostasis and Bone Mineral Density in Children from Ecologically Polluted Regions Before and After Treatmen

N. Kech State Institution “Institute of Hereditary Pathology of NAMS of Ukraine”, Lviv Introduction. One of the decisive mechanisms of the influence of xenobiotics on a human organism is the disturbance of calcium-phosphorous homeostasis and oxidative metabolism of cells due to the changes in the intracellular flow of calcium (Ca) and phosphorus (P), their replacement on specific receptors, and subsequent activation Read More …

Сomparative Evaluation of Bone Mineral Density Based upon the Results of Ultrasound Osteodensitometry, X-ray Osteodensitometry, and Dual-Energy X-ray Absorptiometry Tests in Premenopausal Women with Systemic Lupus Erythematosus

U. Abrahamovych1, O. Abrahamovych1, L. Tsyhanyk1, O. Synenkyi2, S. Guta1 1Danylo Halytsky Lviv National Medical University 2Lviv Regional Clinical Hospital Introduction. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the chronic inflammation and multisystemic damages, accompanied by lesions in osteoarticular system, including secondary osteoporosis (OP) ­ an important risk factor for low­energy fractures. Read More …

Characteristics of Bone Tissue in Postmenopausal Women with Systemic Lupus Erythematosus

О. Аbrahamovych1, U. Аbrahamovych1, L. Tsyhanyk1, О. Synenkyi2, О. Romanyuk1  1Danylo Halytsky Lviv National Medical University 2Lviv Regional Clinical Hospital Introduction. Osteoporosis is one of the most common systemic diseases of the skeletal system that is characterized by decreased bone mass per unit volume, increased bone fragility and risk of fractures. The prevalence of low bone Read More …

Influence of Thyroid Hyperfunction on Bone System Changes

І. Pankiv  Bukovinian State Medical University Introduction. Bone density measurements during the last decade have demonstrated that bone loss is common in patients with overt hyperthyroidism and to a lesser extent in those with subclinical hyperthyroidism, whether caused by nodular goiter or excessive doses of thyroid hormone. Overt hyperthyroidism is associated with accelerated bone remodeling, Read More …

Characteristic of Calcium and Phosphorus Homeostasis and Bone Mineral Density in Children from Ecologically Polluted Regions Before and After Treatment

N. Кеch We investigated 239 children from ecologically polluted regions and 70 children from ecologically clean area. Children’s age is from 3 to 18 years, sex – 48, 0 % boys and 52, 0 % – girls. Level of calcium and phosphorus in the blood and urine in these children before and after the treatment Read More …

Bone Tissue Remodeling Features in Patients with Systemic Lupus Erythematosus Depending on the Degree of Bone Tissue Mineral Density Reduction

U. Abrahamovych Danylo Halytsky Lviv National Medical University Introduction. Osteoporosis is a systemic disease of the skeleton characterized by a decrease in bone mass and a violation of the microarchitectonics of bone tissue, which leads to increased bone fragility and fractures. Today, osteoporosis is one of the priority health problems due to the high prevalence Read More …

Characteristics of Bone System Condition in Children from Clean and Polluted Regions by Indexes of Ultrasound Densitometry

N. Kech State Institution “Institute of Hereditary Pathology of NAMS of Ukraine”, Lviv Introduction. In the opinion of scientists, the thyroid gland occupies the first place by the degree of sensitivity to the action of the negative influence of xenobiotics in a child’s organism then – the liver, lungs, kidneys and bone system. Various organs and systems are responsible for anthropogenic Read More …